SS-31

(Research Use Only) SS‑31 (also known as Elamipretide or D‑Arg‑2′6′‑dimethylTyr‑Lys‑Phe‑NH2) is a synthetic tetrapeptide that has been described in the scientific literature as a mitochondria‑targeting peptide. It is supplied as a lyophilized powder for use as a reference material in laboratory, in‑vitro, and analytical studies conducted by qualified professionals in appropriately equipped research facilities. This product is not a drug and is not intended for human or veterinary use, clinical applications, or any form of in‑vivo administration.

Composition and Form

• Contents: SS‑31, 10 mg per vial (research grade)​

• Form: Lyophilized (freeze‑dried) powder in a sealed vial

• Purity: ≥99% (HPLC / LC‑MS verified; see Certificate of Analysis)​

• Appearance: White to off‑white powder (typical for peptide reference materials)

Structural Information

SS‑31 is a small cell‑permeable tetrapeptide designed to associate with mitochondrial membranes via interaction with selected phospholipids. It has been used in preclinical models as a representative mitochondria‑targeting peptide to investigate mitochondrial structure, bioenergetics, and oxidative stress–related signaling pathways under controlled experimental conditions.

• Example sequence (free base): D‑Arg‑2′,6′‑dimethylTyr‑Lys‑Phe‑NH2

• Other designations: SS‑31, Elamipretide, MTP‑131

Intended Use and Limitations

This product is supplied for Research Use Only (RUO) and is not intended for human or animal consumption. It must not be used for diagnosis, treatment, cure, or prevention of any disease and must not be compounded, ingested, injected, or otherwise administered to humans or animals. Any scientific literature or background information associated with SS‑31 is provided solely to describe its chemical and research characteristics and should not be interpreted as guidance for clinical use, anti‑aging or longevity applications, exercise or performance enhancement, fatigue reduction, cognitive or neuroprotective effects, cardiometabolic benefits, or other health outcomes.

Handling, Storage, and Quality

SS‑31 should be handled using standard laboratory practices appropriate for peptide reference materials, including suitable personal protective equipment and controlled laboratory conditions. Lyophilized vials should be stored according to internal laboratory protocols for peptides, typically in a cool, dry environment protected from light and moisture to help preserve material integrity prior to use.​

Each lot is accompanied by a Certificate of Analysis (COA) providing identity, purity, and analytical data (e.g., HPLC, LC‑MS), allowing researchers to document material quality and suitability for their specific experimental applications. Users are responsible for ensuring that all work with this compound complies with applicable regulations, institutional policies, and ethical standards.