Semax

(Research Use Only) Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4‑7) with a Pro‑Gly‑Pro (PGP) extension at the C‑terminus, supplied as a lyophilized powder for research applications. It is intended solely as a reference material for laboratory, in‑vitro, and analytical studies conducted by qualified professionals in appropriately equipped research facilities. This product is not a drug and is not intended for human or veterinary use, clinical applications, or any form of in‑vivo administration

Structural Information

Semax is a short polypeptide analog of the ACTH(4‑7) fragment with an added PGP sequence that has been described in the scientific literature as a synthetic derivative of endogenous adrenocorticotropic hormone fragments. It has been studied in preclinical and clinical research settings to investigate peptide stability, peptide–receptor interactions, and neuropeptide‑related signaling mechanisms under controlled experimental conditions.​

• Molecular formula: C39H54N10O10S​

• Molecular weight: 854.99 g/mol​

• Other designations: ACTH(4‑7)‑PGP, HY‑P1146​

Intended Use and Limitations

This product is supplied for Research Use Only (RUO) and is not intended for human or animal consumption. It must not be used for diagnosis, treatment, cure, or prevention of any disease and must not be compounded, ingested, injected, or otherwise administered to humans or animals. Any scientific literature or background information associated with Semax is provided solely to describe its chemical and research characteristics and should not be interpreted as guidance for clinical use, nootropic or cognitive enhancement, anxiety or mood modulation, stroke or neuroprotection, cardiovascular support, or other health‑related outcomes.​

Handling, Storage, and Quality

Semax should be handled using standard laboratory practices appropriate for peptide reference materials, including suitable personal protective equipment and controlled laboratory conditions. Lyophilized vials should be stored according to internal laboratory protocols for peptides, typically in a cool, dry environment protected from light and moisture to help preserve material integrity prior to use.​

Each lot is accompanied by a Certificate of Analysis (COA) providing identity, purity, and analytical data (e.g., HPLC, mass spectrometry), allowing researchers to document material quality and suitability for their specific experimental applications. Users are responsible for ensuring that all work with this compound complies with applicable regulations, institutional policies, and ethical standards.