PT-141 (Bremelanotide)

PT‑141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α‑melanocyte‑stimulating hormone (α‑MSH), supplied as a lyophilized powder for research applications. It is intended solely as a reference reagent for laboratory, in‑vitro, and analytical studies conducted by qualified professionals in appropriately equipped research facilities. This product is not a drug and is not intended for human or veterinary use, clinical applications, or any form of in‑vivo administration.

Structural Information

PT‑141 is a synthetic melanocortin receptor agonist derived from α‑MSH, with activity reported at melanocortin receptors including MC3R and MC4R. It is used in preclinical models to study melanocortin receptor pharmacology, including receptor binding, intracellular cAMP signaling, and related neuroendocrine pathways under controlled experimental conditions.

• Molecular formula: C50H68N14O10

• Molecular weight: ~1025.2 g/mol

Intended Use and Limitations

This product is supplied for Research Use Only (RUO) and is not intended for human or animal consumption. It must not be used for diagnosis, treatment, cure, or prevention of any disease and must not be compounded, ingested, injected, or otherwise administered to humans or animals. Any scientific literature or background information associated with PT‑141 is provided solely to describe its chemical and research characteristics and should not be interpreted as guidance for clinical use, sexual or libido‑related applications, erectile function, arousal, mood, appetite/weight effects, or other health or cosmetic outcomes.

Handling, Storage, and Quality

PT‑141 should be handled using standard laboratory practices appropriate for peptide reference materials, including suitable personal protective equipment and controlled laboratory conditions. Lyophilized vials should be stored according to internal laboratory protocols for peptides, typically in a cool, dry environment protected from light and moisture to help preserve material integrity prior to use.

Each lot is accompanied by a Certificate of Analysis (COA) providing identity, purity, and analytical data (e.g., HPLC, mass spectrometry), allowing researchers to document material quality and suitability for their specific experimental applications. Users are responsible for ensuring that all work with this compound complies with applicable regulations, institutional policies, and ethical standards.